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Researchers at Oxford University restricted the dietary intake of hundreds of patients to calories a day for two months under the Cambridge Weight Plan and found that, nearly one year on, they had lost three times more weight than those on other diets and, crucially, they had kept the weight off. The findings appear to fly in the face of previous suggestions that crash dieting leads to a yo-yo effect whereby people lose large amounts of weight but then pile it back on again. A report on the findings was published in the British Medical Journal yesterday and co-author Professor Paul Aveyard, GP and professor of behavioural medicine at Oxford, says the quick weight loss is what kept participants motivated. After 12 months the participants had lost an average 1. Three times as many patients – 45 per cent – saw their weight drop by at least 10 per cent on the meal replacement programme. The authors added that 38 per cent of participants stayed on the meal replacement plan, paying for products and receiving support, even though it was funded only for six months. An independent expert says that this suggests participants did not find sticking with meal replacements too arduous but warned that complete change is necessary to maintain a healthy lifestyle long term. Total diet replacement programmes are designed for people who are obese or seriously obese, with a body mass index BMI of more than 30, who have been unable to lose weight despite changes to diet and lifestyle. In this study, of people from 10 GP practices in Oxfordshire, half followed the Cambridge Weight Plan programme for eight weeks – limiting intake to calories per day by replacing food with specially formulated drinks, soups and snacks.